Affiliation changes for 2015

By major league team:

Arizona: mid-A from South Bend to Kane County
Atlanta: high-A from Lynchburg to Carolina
Chicago Cubs: high-A from Daytona Beach to Myrtle Beach
: mid-A from Kane County to South Bend
:short-A from Boise to Eugene
Cincinnati: high-A from Bakerfield to Daytona (confusingly giving them both Dayton and Daytona)
Cleveland: high-A from Carolina to Lynchburg
Colorado: AAA from Colorado Springs to Albuquerque (!)
: short-A from Tri-Cities to Boise
Houston: AAA from Oklahoma City to Fresno
LA Dodgers: AAA from Albuquerque to Oklahoma City
: AA from Chattanooga to Tulsa.
The Dodgers stake a territorial claim to the Sooner State.
Milwaukee: AAA from Nashville to Colorado Springs
: AA from Huntsville to Biloxi
Minnesota: AA from New Britain to Chattanooga
NY Yankees: add Pulaski, Appalachian League
Oakland: AAA from Sacramento to Nashville
Pittsburgh: short-A from Jamestown to West Virginia (Morgantown). They already have a team in the SAL that calls itself West Virginia, which plays out of Charleston. That’s even more confusing than the Reds.
San Diego: short-A from Eugene to Tri-Cities
San Francisco: AAA from Fresno to Sacramento
Seattle: high A from High Desert to Bakersfield
Seattle: drops Rookie team in Pulaski
Texas: high A from Mytle Beach to High Desert

By minor league:
AAA
PCL
Albuquerque flips from the Dodgers to the Rockies
Colorado Springs goes from Colorado to Milwaukee
Fresno loses the Giants, but gains Astros
Nashville changes from Milwaukee to Oakland
Oklahoma City switches from Houston to the LA Dodgers
Sacramento changes from Oakland to San Francisco
AA
Eastern
New Britain changes from Minnesota to Colorado
Southern
Biloxi is a new team, for the Brewers
Chattanooga from LA Dodgers to Twins
Huntsville is abandoned by the Brewers
Texas
Tulsa changes from Colorado to the Dodgers
High A
Carolina
Carolina Mudcats go from Indians to Braves
Lynchburg goes from Braves to Indians
Myrtle Beach from Texas to the Cubs
California
Bakersfield changes from Cincinnati to Seattle
High Desert changes from Seattle to Texas
Florida
Daytona goes from the Cubs to Reds
Mid-A
Midwest
Kane County changes from Cubs to Diamondbacks
South Bend changes from Diamondbacks to Cubs
Short-A
New York-Penn
Jamestown is abandoned by the Pirates
West Virginia Black Bears is a new Pirate affiliate in Morgantown
Northwest
Boise changes from Cubs to Colorado
Eugene flips from San Diego to the Cubs
Tri-Cities goes from Colorado to San Diego
Rookie
Appalachian
Pulaski changes from Seattle to NY Yankees

Two totally new teams (Biloxi and West Virginia U.)
And two departing:
Huntsville, which had essentially no baseball history prior to getting a AA team, the Stars, in 1985. Prior to that, they had only had a class D team, which existed for the 1930 season in the Georgia-Alablam League.
Jamestown, which has had a team for all but six years since 1939; there were short gaps in 1958-60 and 1974-76. The stadium dates from 1941.